Mushroom Extract Helpful In Treating HPV

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A Japanese mushroom extract appears to be effective for the eradication of human papillomavirus (HPV), according to a pilot clinical trial. The results were presented at the 11th International Conference of the Society for Integrative Oncology in Houston today.  
 
Ten HPV-positive women were treated orally with the extract, AHCC (active hexose correlated compound) once daily for up to six months. Five achieved a negative HPV test result – three with confirmed eradication after stopping AHCC – with the remaining two responders continuing on the study.
 
Currently, there is no effective medicine or supplement to treat HPV, which is associated with more than 99 percent of cervical cancer cases. According to the Centers for Disease Control and Prevention, several other cancers are related to HPV, including 95 percent of anal cancer, 60 percent of oropharyngeal, 65 percent of vaginal cancer, 50 percent of vulvar cancer and 35 percent of penile cancer.
 
AHCC is a readily available nutritional supplement that works to improve the innate immune system. Human and preclinical studies have shown that AHCC increases the number and/or activity of Natural Killer (NK) cells, dendritic cells and cytokines, which help the body fight off infections and block tumor growth.
 
Since AHCC is a nutritional supplement with no side effects and other immune modulating benefits, the researchers plan on using six months of treatment in a phase II clinical study to have consistent study treatment plan.
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