Using Stem Cells To Grow New Hair

Using Stem Cells To Grow New Hair
Scientists have used iPSCs to grow new hair.
(Credit: Sanford-Burnham Medical Research Institute)
In a new study, researchers have used human pluripotent stem cells to generate new hair. The study represents the first step toward the development of a cell-based treatment for people with hair loss. In the United States alone, more than 40 million men and 21 million women are affected by hair loss. The research was published online in PLOS One.

The research team developed a protocol that coaxed human pluripotent stem cells to become dermal papilla cells. They are a unique population of cells that regulate hair-follicle formation and growth cycle. Human dermal papilla cells on their own are not suitable for hair transplants because they cannot be obtained in necessary amounts and rapidly lose their ability to induce hair-follicle formation in culture.

The next step is to transplant human dermal papilla cells derived from human pluripotent stem cells back into human subjects.
 
Based on materials originally posted by Sanford-Burnham Medical Research Institute.