A new study shows that withaferin A, a component of Withania somnifera (winter cherry) plant extract, may hold promise as a new treatment for non-Hodgkin’s lymphoma. The research was published in the journal Cancer Biology and Therapy.
Winter cherry extract was used in traditional Ayurvedic Indian medicine for thousands of years before it caught the interest of researchers. The researchers found found that withaferin A prevented the lymphoma cells from dividing and ultimately killed them. Specifically, they found withaferin A directly targeted a signaling pathway in the cancer it needs to survive.
“It may be possible to develop orally administered versions of withaferin A that could be used in lymphoma patients with fewer side effects than current chemotherapy regimens,” the researchers said.
Because withaferin A shows promise in treating non-Hodgkin lymphoma, the researchers is now testing the chemical on chronic lymphocytic leukemia cells.
Based on material originally posted by University of Kentucky.